周 天，顾亦昂，赵晓庆

（颇尔（中国）有限公司，上海 201210）

摘 要：探讨颇尔1.4μm，MembraloxGP（GradientPermeability，梯度渗透）陶瓷膜应用于传统益生菌发酵液浓缩分 离，替代传统离心机离心分离工艺的可行性。整个实验过程中，对7种不同的益生菌种采用了单级浓缩分离，总固 体悬浮物含量最高可以达到54%（w/w），平均通量最大可达129kg/m2/hr。相较于单级浓缩，二级浓缩的优势在于 更高的浓缩比，比较乳双歧杆菌的单极和二级浓缩液，二级浓缩液固体悬浮物含量达到80%，益生菌回收率同样可 以达到99%以上。本论文研究探索陶瓷膜浓缩分离工艺的独特优势，为益生菌传统浓缩分离工艺的升级开拓了新 的思路和视野。

关键词：益生菌；浓缩；陶瓷膜；错流

Feasibility Study on the Application of Ceramic Membrane Filtration in Probiotic Concentration Process

ZHOU Tian，GU Yi-ang，ZHAO Xiao-qing

（Pall（China）Co.，Ltd，Shanghai 201210，China）

Abstract: The feasibility of using a Pall 1.4μm Membralox GP（Gradient Permeability）ceramic membrane for the concentration and separation of traditional probiotic fermentation broth，replacing traditional centrifuge separation processes，was studied. Throughout the entire experiment，single- stage concentration separation was used for 7 different probiotic species；with a maximum total solid content of 54%（w/w）and an average flux of up to 129kg/m2/ hr. Compared to single-stage concentration，the advantage of two-stage concentration lies in a higher concentration ratio. Comparing the single-stage and two-stage concentrations of Bifidobacterium lactis，the solid content of the two stage concentration reaches 80% ，and the recovery rate of probiotics can also reach over 99% . From a new perspective，the innovative introduction of ceramic membrane concentration and separation technology has opened up new ideas and perspectives for upgrading traditional probiotic concentration and separation processes.

Key words: probiotic；concentration；ceramic；crossflow

中图分类号：TS202              文献标志码：A                 文章编号：1007-7871（2025）01-0029-04

2025，Vol.28，No.1